2004年度

Antioxidative effects of glycosyl-ascorbic acids synthesized by maltogenic amylase to reduce lipid oxidation and volatiles production in cooked chicken meat.
Lee SB, Nam KC, Lee SJ, Lee JH, Inouye K, Park KH. (2004) Biosci. Biotechnol. Biochem. 68; 36-43


C-3 Epimerization of Vitamin D3 Metabolites and Further Metabolism of C-3 Epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through C-1α or C-24 hydroxylayion.
Kamao M, Tatematsu S, Hatakeyama S, Sakaki T, Sawada N, Inouye K, Ozono K, Kubodera N, Reddy GS, Okano T. (2004) J. Biol. Chem. 279; 15897-15907


Metabolism of polychlorinated dibenzo-p-dioxins by cytochrome P450 BM-3 and its mutant.
Sulistyaningdyah WT, Ogawa J, Li QS, Shinkyo R, Sakaki T, Inouye K, Schmid RD, Shimizu S. (2004) Biotechnol. Lett. 26; 1857-1860


Inhibitory effects of alcohols on the activity of human matrix metalloproteinase 7 (matrilysin).
Muta Y, Oneda H, Inouye K. (2004) Biosci. Biotechnol. Biochem. 68; 2649-2652


Metabolism of vitamin D by human microsomal CYP2R1.
Shinkyo R, Sakaki T, Kamakura M, Ohta M, Inouye K.(2004) Biochem. Biophys. Res. Commun. 324; 451-457


Purification and characterization of mouse CYP27B1 overproduced by an Escherichia coli system coexpressing molecular chaperonins GroEL/ES.
Uchida E, Kagawa N, Sakaki T, Urushino N, Sawada N, Kamakura M, Ohta M, Kato S, Inouye K. (2004) Biochem. Biophys. Res. Commun. 323; 505-511


Detection of antigen-antibody reaction using a fluorescent probe and its application to homogeneous competitive-type immunoassay for insulin.
Oneda H, Inouye K. (2004) Biosci. Biotechnol. Biochem. 68; 2190-2192


Inhibitory effects of lignans on the activity of human matrix metalloproteinase 7 (matrilysin).
Muta Y, Oyama S, Umezawa T, Shimada M, Inouye K. (2004) J. Agric. Food. Chem. 52; 5888-5894


Metabolism of A-ring diastereomers of 1alpha,25-dihydroxyvitamin D3 by CYP24A1.
Kusudo T, Sakaki T, Abe D, Fujishima T, Kittaka A, Takayama H, Hatakeyama S, Ohta M, Inouye K. (2004) Biochem. Biophys. Res. Commun. 321; 774-782


Substrate-dependent activation of thermolysin by salt.
Oneda H, Muta Y, Inouye K. (2004) Biosci. Biotechnol. Biochem. 68; 1811-1813


Sequential metabolism of 2,3,7-trichlorodibenzo-p-dioxin (2,3,7-triCDD) by cytochrome P450 and UDP-glucuronosyltransferase in human liver microsomes.
Kasai N, Sakaki T, Shinkyo R, Ikushiro S, Iyanagi T, Kamao M, Okano T, Ohta M, Inouye K. (2004) Drug. Metab. Dispos. 32; 870-875


Insights into the reaction mechanism of the coagulation of soy protein isolates induced by subtilisin carlsberg.
Nagai K, Inouye K. (2004) J. Agric. Food. Chem. 52; 4921-4927


Conversion of vitamin D3 to 1alpha,25-dihydroxyvitamin D3 by Streptomyces griseolus cytochrome P450SU-1.
Sawada N, Sakaki T, Yoneda S, Kusudo T, Shinkyo R, Ohta M, Inouye K. (2004) Biochem. Biophys. Res. Commun. 320; 156-164


Homology modeling of human 25-hydroxyvitamin D3 1alpha-hydroxylase (CYP27B1) based on the crystal structure of rabbit CYP2C5.
Yamamoto K, Masuno H, Sawada N, Sakaki T, Inouye K, Ishiguro M, Yamada S. (2004) J. Steroid. Biochem. Mol. Biol. 89-90; 167-171


Novel metabolism of 1 alpha,25-dihydroxyvitamin D3 with C24-C25 bond cleavage catalyzed by human CYP24A1.
Sawada N, Kusudo T, Sakaki T, Hatakeyama S, Hanada M, Abe D, Kamao M, Okano T, Ohta M, Inouye K.(2004) Biochemistry. 43; 4530-4537


Inhibitory effect of 0.19 alpha-amylase inhibitor from wheat kernel on the activity of porcine pancreas alpha-amylase and its thermal stability.
Oneda H, Lee S, Inouye K. (2004) J. Biochem. (Tokyo) 135; 421-427


Analysis of autodegradation sites of thermolysin and enhancement of its thermostability by modifying Leu155 at an autodegradation site.
Matsumiya Y, Nishikawa K, Aoshima H, Inouye K, Kubo M. (2004) J. Biochem. (Tokyo) 135; 547-553