2003年度

Metabolic pathways of dioxin by CYP1A1: species difference between rat and human CYP1A subfamily in the metabolism of dioxins.
Shinkyo R, Sakaki T, Ohta M, Inouye K. (2003)Arch. Biochem. Biophys. 409; 180-187


Lysyl-tRNA Synthetase from Bacillus stearothermophilus: The Trp314 Residue is Shielded in a Non-polar Environment and is Responsible for the Fluorescence Changes Observed in the Amino Acid Activation Reaction.
Takita T, Nakagoshi M, Inouye K, Tonomura B. (2003) J.Mol.Biol. 325; 677-695


Differential scanning calorimetry of the effects of Ca2+ on the thermal unfolding of Pseudomonas cepacia lipase.
Tanaka A, Sugimoto H, Muta Y, Mizuno T, Senoo K, Obata H, Inouye K. (2003) Biosci. Biotechnol. Biochem. 67; 207-210


Molecular cloning and characterization of CYP719, a methylenedioxy bridge-forming enzyme that belongs to a novel P450 family, from cultured Coptis japonica cells.
Ikezawa N, Tanaka M, Nagayoshi M, Shinkyo R, Sakaki T, Inouye K. (2003) J. Biol. Chem. 278; 38557-38565


Metabolism of 26,26,26,27,27,27-F6-1α,25-dihydroxyvitamin D3 by CYP24: species-based difference between humans and rats.
Sakaki T, Sawada N, Abe D, Komai K, Shiozawa S, Nonaka Y, Nakagawa K, Okano T, Ohta M, Inouye K. (2003) Biochem. Pharmacol. 65; 1957-1965


Inhibitory effects of green tea catechins on the activity of human matrix metalloproteinase 7 (matrilysin).
Oneda H, Shiihara M, Inouye K. (2003) J. Biochem. (Tokyo) 133; 571-576


Purification and characterization of purple acid phosphatase PAP1 from dry powder of sweet potato.
Kusudo T, Sakaki T, Inouye K. (2003) Biosci. Biotechnol. Biochem. 67; 1609-1611


Generation of 2,3,7,8-TCDD-metabolizing enzyme by modifying rat CYP1A1 through site-directed mutagenesis.
Shinkyo R, Sakaki T, Takita T, Ohta M, Inouye K. (2003) Biochem. Biophys. Res. Commun. 308; 511-517


Characterization of p-aminobenzamidine-based sorbent and its use for high-performance affinity chromatography of trypsin-like proteases.
Nakamura K, Suzuki T, Hasegawa M, Kato Y, Sasaki H, Inouye K. (2003) J. Chromatogr. A. 1009; 133-139


Metabolism of 20-epimer of 1α,25-dihydroxyvitamin D3 by CYP24: species-based difference between humans and rats.
Kusudo T, Sakaki T, Abe D, Fujishima T, Kittaka A, Takayama H, Ohta M, Inouye K. (2003) Biochem. Biophys. Res. Commun. 309; 885-892


Effect of nitration on the activity of bovine erythrocyte Cu,Zn-superoxide dismutase (BESOD) and a kinetic analysis of its dimerization-dissociation reaction as examined by subunit exchange between the native and nitrated BESODs.
Oneda H, Inouye K. (2003) J. Biochem. (Tokyo) 134; 683-690